For every dollar invested in vaccination, $16 is expected to be saved in healthcare costs and the lost wages and lost productivity caused by illness and death. And when the analysis went beyond the restricted cost-of-illness approach and looked at broader economic benefits, it found the net benefit-cost ratio was more than twice as high—reaching 44 times, with an uncertainty range of 27 to 67. The highest rewards were for averting measles: a 58-fold return.
