The serum triglyceride (TG), when unloaded of its fat at the adipose tissue, becomes the small dense LDL. Therefore, the TG:HDL (high-density lipoprotein) ratio—the real ratio of bad to good cholesterol—is the best biomarker of small dense LDL, the best biomarker of cardiovascular disease, and the best surrogate marker of insulin resistance and metabolic syndrome.
