A task as grand as revolutionising science was never going to be straightforward. There’ll be trial, error and, appropriately, experimentation along the way. This isn’t just about discarding some faulty theory, like geocentrism, or phlogiston, or alchemy, or any of the menagerie of incorrect ideas that litter the history of science. This is about root-and-branch (or lab-and-journal) reform of the way we do research, and of scientific culture – an attempt to master the faults and biases that have crept in, largely unnoticed. The world is rightly proud of where science has brought us. To retain
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