I include PREDIMED here not because it was a particularly bad example of hype, but because it’s an example of some of the best research in an extraordinarily hyped field – and because it shows us how even a poster child for rigour might be subject to hidden flaws. Rather like psychology, nutritional epidemiology is hard. An incredibly complex physiological and mental machinery is involved in the way we process food and decide what to eat; observational data are subject to enormous noise and the vagaries of human memory; randomised trials can be tripped up by the complexities of their own
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