senescence is the cumulative effect of things that happen to our bodies over time that may be harmful or cause difficulties for us. Cellular senescence is the specific case of our cells losing the ability to repair themselves and replicate. Much of what we recognize as the undesirable effects of aging is caused by cellular senescence—wrinkles, memory loss, and a lowered immune-system response. This is paralleled by a progressive decline in the ability of most organs to repair and recover from injury and disease. Many—perhaps most—older adults are living with chronic low-grade inflammation and
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