If, for whatever reason, a steam engine is unable to eliminate its entropic buildup, sooner or later it will redline and fail. A similar fate will befall a brain that, for whatever reason, cannot clear away the entropic waste that its functioning continually produces. And a brain that fails is a brain that no longer thinks. Therein lies the potential challenge to the durability of brain-based thought. As the universe progresses ever further into the future, will brains maintain the capacity to jettison the waste heat they produce?

