Naturally occurring compounds known as goitrogens, which are found in soybeans, flaxseeds, and raw cruciferous vegetables (broccoli, Brussels sprouts, cauliflower, and cabbage), counteract the activity of iodine. A diet high in goitrogens can cause hypothyroidism if the diet is too low in iodine. But as long as your diet is adequate in iodine, there is no reason to avoid soyfoods or other sources of goitrogens.