To help cope, 13 percent of us over the age of 12 will use antidepressants, most often selective serotonin reuptake inhibitors, also known as SSRIs. These drugs have been lifesavers for millions, especially those with severe depression and other serious conditions. But less than half the patients who take them get any benefits.* “I keep asking myself,” says Feinstein, “Is this the best we can do?”

