The Rules of Contagion: Why Things Spread - and Why They Stop
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According to the SIR model, outbreaks need three things to take off: a sufficiently infectious pathogen, plenty of interactions between different people, and enough of the population who are susceptible. Near the critical herd immunity threshold, a small change in one of these factors can be the difference between a handful of cases and a major epidemic.
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R therefore depends on four factors: the duration of time a person is infectious; the average number of opportunities they have to spread the infection each day they’re infectious; the probability an opportunity results in transmission; and the average susceptibility of the population.
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R = Duration × Opportunities × Transmission probability × Susceptibility