Your brain uses something like 25 percent of your body’s cholesterol, and many of your hormones are made from it. Cholesterol is integral to the structure of every cell in your body. You can easily find studies that link low cholesterol to depression, violence, suicide, and neurodegenerative diseases. Some studies report that people tend to die younger if they have low cholesterol. Some cancers have been linked to low cholesterol. Infectious disease can be more difficult to fight when cholesterol levels are low.