Gage’s colleague Gerd Kempermann raised aging mice in enriched environments, filled with mice toys such as balls, tubes, and running wheels, for only forty-five days. When Kempermann sacrificed the mice and examined their brains, he found they had a 15 percent increase in the volume of their hippocampi and forty thousand new neurons, also a 15 percent increase, compared with mice raised in standard cages.

