Jennifer Frary

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An addict experiences cravings because his plastic brain has become sensitized to the drug or the experience. Sensitization is different from tolerance. As tolerance develops, the addict needs more and more of a substance or porn to get a pleasant effect; as sensitization develops, he needs less and less of the substance to crave it intensely. So sensitization leads to increased wanting, though not necessarily liking. It is the accumulation of ΔFosB, caused by exposure to an addictive substance or activity, that leads to sensitization.
The Brain That Changes Itself: Stories of Personal Triumph from the Frontiers of Brain Science
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