When people were switched to a low-salt diet, the levels in their blood of the gut hormone ghrelin dropped, and when shifted to a high-salt diet, their ghrelin levels shot up.1927 Ghrelin, the so-called hunger hormone I discussed in the High in Fiber-Rich Foods section, is the target of attempts by drug companies to create an anti-obesity vaccine,1928 but we may be able to help block its action naturally by lowering our sodium intake.