A man’s soul doth wrong and disrespect itself first and especially, when as much as in itself lies it becomes an aposteme, and as it were an excrescency of the world, for to be grieved and displeased with anything that happens in the world, is direct apostacy from the nature of the universe; part of which, all particular natures of the world, are. Secondly, when she either is averse from any man, or led by contrary desires or affections, tending to his hurt and prejudice; such as are the souls of them that are angry. Thirdly, when she is overcome by any pleasure or pain.
translation: according to stoicism the soul harms itself by 1) resisting the natural order of the universe. 2) harboring negative emotions— ex: anger, hatred, fear, envy. 3) being controlled by pleasure or pain. 4) dishonesty. 5) acting without purpose— so align your soul with reason, truth, and the natural order