Although 10–30 per cent of all UK patients going to see their doctor for any reason report substantial fatigue lasting for more than a few weeks (15–27 per cent in the US), studies have indicated that a diagnosis of chronic fatigue syndrome is made in only a small minority of these cases. CFS appears to be more common in women than men. A variety of explanations have been put forward for this, in particular changes in the role of women, with increased demands and expectations. Although fatigue is relatively uncommon during childhood, its incidence rises during adolescence. Chronic fatigue
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