Second, Chalcedon is known, perhaps most famously, for the so-called “four negatives.” When the council confessed that there is a perfect unity between the divine and human natures in Christ, it said they are united in such a way as to be “without confusion, without change, without division, without separation.” In other words, the council said that we cannot mix up the two natures of Christ; that was the heresy of the monophysites.