Inflammation is essentially the heat of battle as the body defends itself from damage. Blood vessels in the vicinity of an injury dilate, allowing more blood to flow to the site, bringing with it white blood cells to fight off invaders. That causes the site to swell, increasing the pressure on surrounding nerves, resulting in tenderness. Unlike red blood cells, white blood cells can leave the circulatory system to pass through surrounding tissues, like an army patrol searching through jungle. When they encounter an invader,