“Like, in Appalachia—if anyone wants to take this substance abuse problem seriously, they will build an interstate and a decent highway system through the area so that people can build businesses there. It’s ridiculous to think that treatment or greater law enforcement is going to have any effect on the drug abuse problem there, because it’s driven by core economic and life issues. It’s a depressing place to live. And people don’t like to stay depressed, so they do things to get away from it.”