As conceived from Darwin to the present, natural selection “selects,” or acts to preserve, those random variations that confer a fitness or functional advantage upon the organisms that possess them. But it “selects” only after such advantageous variations or mutations have arisen. Thus, selection does not cause novel variations; rather, it sifts what is delivered to it by the random changes (i.e., mutations) that do cause variations. This has been neo-Darwinian orthodoxy for many decades. All this means that natural selection does nothing to help generate functional DNA base (or amino-acid)
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