I began this book by describing my March 2016 debate with Lawrence Krauss at the University of Toronto. Krauss, and later Richard Dawkins in defense of Krauss, claimed that my critique misrepresented the evolutionary mechanism as a purely random process. Instead, both Krauss and Dawkins insisted, in Dawkins’s words, that “natural selection is a nonrandom process,” implying that it presumably could succeed in finding the extremely rare functional arrangements of nucleotide bases and amino acids within the space of possible arrangements in available evolutionary time.