Later, worries about neo-Darwinism spread to evolutionary biologists themselves.10 Over the past three decades, many evolutionary biologists have challenged a key tenet of the neo-Darwinian synthesis, namely, the idea that small-scale microevolutionary changes can be extrapolated to explain large-scale macroevolutionary innovations. For the most part, microevolutionary changes (such as variation in color) merely use or express existing genetic information, while the macroevolutionary change necessary to assemble new organs or whole body plans requires the production of new genetic information.
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