He gave two cider, two sulfuric acid, two vinegar, two seawater, two a mixture of nutmeg and garlic, and finally, gave two lemons and oranges. The results were remarkable—of the entire group, the patients who received lemons and oranges were fit for duty within a week and began nursing the others to health. This was, for most intents and purposes, the first “controlled” clinical trial performed in human history.

