excess body fat raises the risk of most cancers, including esophageal, stomach, colorectal, liver, gallbladder, pancreatic, breast, uterine, ovarian, kidney, brain, thyroid, and bone marrow (multiple myeloma) cancers.290 Why? It could be due to the chronic inflammation that comes with obesity 291 or the high insulin levels due to insulin resistance.292 (Besides controlling blood sugars, insulin is a potent growth factor that can promote tumor growth.293) In women, it could also be the excess estrogen.294