When people feel crappy on a regular basis, quite a few of them self-medicate. Thirty percent of all medications consumed in the United States are taken to manage some form of distress. For these sufferers, their predictions are regularly not calibrated to their bodies’ actual expenditures, likely because their brain is misestimating the cost. So they feel miserable and take medication, or they turn to alcohol or certain street drugs like opiates.3
