When something occurs that is not intended-when the actual outcome, as interpreted, does not match the desired outcome, as posited-the hippocampus shifts mode and prepares to update cortical memory storage. Behavioral control shifts from the cortex to the limbic system-apparently, to the amygdala, which governs the provisional determination of the affective significance of unpredictable events, and has powerful output to centers of motor control. 111 This shift of control allows the activation of structures governing orienting, heightened intensity of sensory processing and exploration.
