the clamor in my head soured, becoming what is known in mood disorder parlance as a “mixed episode.” Such episodes occur when a person is experiencing symptoms of both a manic and a depressive phase, such as in episodes of agitated depression. It is considered a dangerous state to be in if that person is suicidal; a severely depressed person will find it hard to summon enough energy to plan and execute a suicide, but a severely depressed person shot through with norepinephrine is reckless enough to do both.

