Jiří Charvát

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When an expected reward fails to materialize, the dopamine system shuts down. In scientific terms, when the dopamine system is at rest, it fires at a leisurely three to five times per second. When it’s excited, it zooms up to twenty to thirty times per second. When an expected reward fails to materialize, the dopamine firing rate drops to zero, and that feels terrible.
The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity―and Will Determine the Fate of the Human Race
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