Melatonin benefits our mitochondria in numerous ways, including: Preventing free radical damage directly in the actual mitochondria299,300 (which is quite unique to melatonin since virtually all other “antioxidants” cannot do this). Regulation of mitochondrial bioenergetic function and maintaining respiratory complex activities, electron transport chain, and ATP production in mitochondria.301 Acting as a neuroprotectant in the brain, preventing the kind of oxidative stress/nitrosative stress-induced mitochondrial dysfunction seen in experimental models of Parkinson’s, Alzheimer’s, and
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