A patient taking Phenobarbital (an anti-epileptic drug) was prescribed 0.5gr per day (32.4 milligrams), and this was mistaken for 0.5 grams per day (500 milligrams). After three days on over fifteen times their normal dose, the patient started to have respiratory problems. Thankfully, when they were taken off the dose, they made a full recovery. This was a case of no grain, no pain.