breast cancer incidence rates in the United States have increased by roughly 0.5 percent annually since the premature termination of the WHI’s trial in 2002, even though hormone use has remained low;46 according to the FDA, in 2023, 82 percent of American women over 45 reported at least one menopausal symptom, but only 10.5 percent had used any form of menopausal hormone therapy.47 And third, breast cancer usually takes from 9 to 16 years to become clinically identifiable.