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In 2020, the National Academies of Science confirmed the unreliability of compounded bioidentical hormones (cBHT). After 21 months of data collection and analysis, the investigating committee concluded: “Given the paucity of data on the safety and effectiveness of cBHT… there is insufficient evidence to support the overall clinical utility of cBHT as treatment for menopause.”
Estrogen Matters: Why Taking Hormones in Menopause Can Improve Women's Well-Being and Lengthen Their Lives -- Without Raising the Risk of Breast Cancer (2024 Revised and Updated Edition)
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