When other researchers reversed this process and flooded the reward system of the brain with dopamine, animals performed habits at breakneck speed. In one study, mice received a powerful hit of dopamine each time they poked their nose in a box. Within minutes, the mice developed a craving so strong they began poking their nose into the box eight hundred times per hour. (Humans are not so different: the average slot machine player will spin the wheel six hundred times per hour.)