My headache is gone now, but why? Was it the aspirin I took? The food I ate? The good news I heard? These queries take us to the top rung of the Ladder of Causation, the level of counterfactuals, because to answer them we must go back in time, change history, and ask, “What would have happened if I had not taken the aspirin?” No experiment in the world can deny treatment to an already treated person and compare the two outcomes, so we must import a whole new kind of knowledge.