in 1951 they began a prospective study, for which they sent out questionnaires to 60,000 British physicians about their smoking habits and followed them forward in time. (The American Cancer Society launched a similar and larger study around the same time.) Even in just five years, some dramatic differences emerged. Heavy smokers had a death rate from lung cancer twenty-four times that of nonsmokers. In the American Cancer Society study, the results were even grimmer: smokers died from lung cancer twenty-nine times more often than nonsmokers, and heavy smokers died ninety times more often.