Fisher realized that an uncertain answer to the right question is much better than a highly certain answer to the wrong question. If you ask the genie the wrong question, you will never find out what you want to know. If you ask the right question, getting an answer that is occasionally wrong is much less of a problem. You can still estimate the amount of uncertainty in your answer, because the uncertainty comes from the randomization procedure (which is known) rather than the characteristics of the soil (which are unknown).
