The Mayas in the Yucatán Peninsula believed that three evil gods – Ekpetz, Uzannkak and Sojakak – were flying from village to village at night, infecting people with the disease. The Aztecs blamed it on the gods Tezcatlipoca and Xipetotec, or perhaps on the black magic of the white people. Priests and doctors were consulted. They advised prayers, cold baths, rubbing the body with bitumen and smearing squashed black beetles on the sores. Nothing helped.

