Based on 2015 data, the Institute for Health Metrics and Evaluation (IHME) estimates that lead exposure accounts for 494,550 deaths and the loss of 9.3 million disability-adjusted life years due to its long-term effects on health. The IHME also estimates that lead exposure accounts for 12.4 percent of the global burden of developmental intellectual disability, 2.5 percent of the global burden of heart disease, and 2.4 percent of the global burden of stroke.
