Stigma was the real enemy of hope for the drug-addicted, Hadden decided. So to tamp it down, she decided her job was to explain the misunderstood science of addiction: Once a person becomes addicted, he loses his power of choice; his free will becomes hijacked along with the opioid receptors in his brain. When a person’s natural opioids are shut down by the deluge of synthetic ones, she told the audience at the community meeting, it creates a growing tolerance to the drug, making the brain crave ever-larger quantities of opioids just to keep from being violently ill.

