The term immune system was used for the first time in 1967 by Niels Jerne, an immunologist who was trying to reconcile two factions of immunology—those who believed that immunity depended largely on antibodies and those who believed it depended more on specialized cells. Jerne used the word system to unite all the cells and antibodies and organs involved in immunity into one comprehensive whole. This idea that immunity is the product of a complex system of interdependent parts acting in concert is relatively new to science.

