Even more perplexing for the cholesterol activists is the recent finding that in people with FH, blood cholesterol concentration has essentially no predictive value for heart attack or stroke in the next 5–10 years.97 Instead, in order of significance, the following factors increased risk for a cardiovascular event: age (above 60 years), obesity, previous history of CVD, age (30–59 years), overweight, diabetes, use of the drug ezetimibe, high blood pressure, patient on maximum combined therapy, patient on maximum lipid-lowering therapy, male, premature family history of CVD, patient on maximum
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