Besides the high levels of protective antioxidants and polyphenols contained in olive oil and red wine, which have beneficial effects on cellular health, the anti-inflammatory effect of the Mediterranean diet on the body is most often cited. Polyphenols are plant-based compounds found in a variety of foods and beverages. Besides red grapes and olives, many other fruits and vegetables are rich sources of polyphenols, as are coffee, tea, chocolate, and some nuts.

