Mark Gerstein

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This question describes what epidemiologists would call an intervention or a treatment and corresponds to what we measure in a clinical trial. In many cases we may also wish to compare P(L | do(D)) with P(L | do(not-D)); the latter describes patients denied treatment, also called the “control” patients. The do-operator signifies that we are dealing with an intervention rather than a passive observation; classical statistics has nothing remotely similar to it.
The Book of Why: The New Science of Cause and Effect
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