Even people who think it is a fine idea in theory to use knowledge to improve well-being insist it will never work in practice. And the daily news offers plenty of support for their cynicism: the world is depicted as a vale of tears, a tale of woe, a slough of despond. Since any defense of reason, science, and humanism would count for nothing if, two hundred and fifty years after the Enlightenment, we’re no better off than our ancestors in the Dark Ages, an appraisal of human progress is where the case must begin.
