Hiking calms. According to a study published in the Proceedings of the National Academy of Sciences, a ninety-minute walk through a natural area led to lower levels of brooding and obsessive worry. Brain scans of the subjects found that there was decreased blood flow to the subgenual prefrontal cortex. Increased blood flow to this region of the brain is associated with bad moods. Everything from feeling sad about something, to worrying, to major depression seems to be tied to this brain region. Hiking deactivates it.