Criminalization makes it hard for drug users to complain about adulterated products or even share information with other users and interferes with access to treatment. Most heavy drug users who are arrested receive no real drug treatment and are expected to go clean on their own while incarcerated, leading to adverse health effects and even death. Prohibition also forces people to share needles and other drug paraphernalia; the second most prevalent method of HIV transmission in the US today is injection drug users sharing needles.

