The amygdala, a key node in the brain’s stress circuitry, shows dampened activity from a mere thirty or so hours of MBSR practice. Other mindfulness training shows a similar benefit, and there are hints in the research that these changes are traitlike: they appear not simply during the explicit instruction to perceive the stressful stimuli mindfully but even in the “baseline” state, with reductions in amygdala activation as great as 50 percent.

