we might now note that it was, more than a hundred years later, confirmed by the neuroscientist Antonio Damasio, as he explains in his powerful book Descartes’ Error. Damasio discovered that when people have limited or nonexistent emotional responses to situations, whether through injury or congenital defect, their decision making is seriously compromised. They use reason alone—and, it turns out, reason alone is an insufficient guide to action.