In 2002 researchers at Yale University School of Medicine decided to take a look at the data around digoxin, analyzing its effects by sex. Between 1991 and 1996, researchers had carried out randomized trials on heart patients using digoxin. They found that it didn’t affect how long a patient lived, but it did on average reduce their risk of hospitalization. But the Yale team noted that the drug was tested on roughly four times as many men as women, and they didn’t respond identically.
