In molecular biology, an interactome is the whole set of molecular interactions in a particular cell.
The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein–protein interactions, PPIs; or between small molecules and proteins) but can also describe sets of indirect interactions among genes (genetic interactions).
The interactomes based on PPIs should be associated to the proteome of the corresponding species in order to provide a global view ("omic") of all the possible molecular interactions that a protein can present.