Only in recent years, as the dynamism of the individual genome during development and beyond has been recognized (Poduri, Evrony, et al. 2013) and organismal phenotypes have been discovered that represent the integrated output of multiple genomes (e.g., via host–microbiome interactions), have these distinctions again become blurred (Wang, Klipfell, et al. 2011; Brestoff and Artis 2013).